Day 2 :
- Endodontics | Basic Dentistry | Oral and Maxillofacial Surgery | Dental and Oral Health
Location: Manchester Airport Marriott Hotel
Chair
Sim K Singhrao
University of Central Lancashire, UK
Co-Chair
Kashif Hafeez
Royal College of Surgeons, Ireland
Session Introduction
Sim K. Singhrao
University of Central Lancashire, UK
Title: Is periodontal disease a risk factor for developing Alzheimer’s disease?
Time : 10:00-10:30
Biography:
Sim K Singhrao has gained her PhD from Cardiff University, UK. She did her Post-doctoral training from Cardiff University School of Medicine and then from the School of Dentistry. She is currently a Senior Research Fellow at the University of Central Lancashire, exploring the causative relationship of periodontitis and Alzheimer’s disease. She has published more than 60 papers in peer-reviewed journals and 4 book chapters. She is currently serving as an Editorial Board Member for Journal of Alzheimer’s Disease.
Abstract:
Alzheimer’s disease (AD) is a neurodegenerative condition that results in a long-term devastating emotional/psychological impact on their loved ones. The neuropathological hallmarks of AD are the deposition of copious amounts of amyloid beta (Aβ) and hyperphosphorylated tau protein coated neurofi brillary tangles in the brain. For decades, the role of the innate immune system in the etiology of AD was considered less important but the recently discovered infl ammatory genes by Genome-Wide association studies driving infl ammation in this disease has changed this view. Innate immune infl ammatory activity in the AD brain can result from the pathological hallmark Aβ protein as well as from specifi c peripheral microbial infections including the sub-gingival bacterial biofi lms. Oral spirochetes and Porphyromonas gingivalis components such as lipopolysaccharide (LPS), peptidoglycan and genomic DNA have all been detected in the brains of AD following autopsy. The oral pathobionts elicit weak immunostimulatory activity as a consequence of their immune evasion strategies, which aid their survival in the host. The aim of this presentation is to, disseminate new knowledge in the ever expandingfield of dentistry with experimental evidence from human AD brains and from experimental models of periodontitis in the apolipoprotein E(APOE) gene knockout mice. Th e possible contribution, specifi cally of the oral pathobionts P. gingivalis playing a role in infl uencing the development, and progression of AD infl ammatory pathology will be highlighted.
Samantha Pozzi
University of Modena and Reggio Emilia, Italy
Title: An up-date of oral complications in the era of novel agents in onco-haematology
Time : 10:30-11:00
Biography:
Samantha Pozzi has specialized in Haematology. She is an Associate Professor of Internal Medicine at University of Modena and Reggio Emilia, Italy. She is a Teacher of Internal Medicine at the Dental School of University of Modena and Reggio Emilia, Italy. She was a Post-doctoral Researcher at Dana Farber Cancer Institute and Massachusetts General Hospital, USA. She has published clinical research on Bisphosphonate-related osteonecrosis of the jaw (BRONJ) and translational research on bisphosphonates, myeloma and lymphomas. She is Principal Investigator and Co-investigator in several clinical trials in Onco-haematology.
Abstract:
In the era of novel cancer treatments, both cancer doctors and dentists are observing drug related oral toxicities. Hence, awareness and multidisciplinary approach is necessary to improve the management of the patients. Th e oral mucositis which is secondary to chemotherapy, and especially in high-dose chemotherapy during the transplant setting, has now become the focus of several studies. Doctors are also well aware of acute and long term toxicities due to radiation of head and neck. Starting from 2003, Osteonecrosis of the jaw (ONJ) related to the administration of bisphosphonates represented a new challenge in the cancer care. Due to the recognition of the risk and the introduction of preventive strategies and combined therapeutic approaches, the number of new cases and the most severe consequences have become limited. More recently, the introduction of novel anti-cancer drugs and antiresorptive agents highlighted, oral complications with some similarities and some new aspects compared with the chemotherapy-induced mucositis, and bisphosphonate related ONJ. In particular, target therapies like everolimus, an m-TOR inhibitor, and EGFR-inhibitors induce mucosal lesions, ranging from mucositis to aphthous-like ulcers. Whereas, the novel antiresorptive agent denosumab, an anti-RANKL moncolonal antibody, and antiangiogenetic drugs have demonstrated a potential risk in inducing ONJ, increasing the number of drugs involved in bone damage of the mandible and maxilla. In the current presentation, we will present an up-date of the oral complications in the era of novel cancer treatments in order to inform the specialists, promote a multidisciplinary approach and improve patients care.
Walid Odeh
German board in oral Implantology, Jordan
Title: Difficult cases and their clinical solution
Time : 11:00-11:30
Biography:
Walid Odeh has completed his BDS from Nisantas Ozal Yuksek Okulu, Marmara University, Turkey. Beside that he has a Master’s degree in Orthodontics from Baghdad University. He is a Fellow of ICCDE (International College of Dental Education). He is a member of: ICOI (International Congress of Oral Implantologist); AAID (American Academy of Implant Dentistry; Austrian, Turkish Jordanian and Egyptian Implant Association; European Esthetic Association; WFO (World Federation of Orthodontics); AOS (Arab Orthodontic Society); DGZI (German Implant Association); ADA (American Dental Association) and; AAAM (American Academy of Aesthetic Medicine). He is treating so many cases of TMJ disorder and gummy smile by Botox, besides participating in many international conferences as a Lecturer in many countries like USA, Germany, Jordan, Taiwan, Hong Kong and many Arab countries.
Abstract:
I believe that, an orthodontist is not only a specialist dentist; he must have knowledge and interest in art, as dentistry is not about teeth treatment but also aesthetic of the face. In some clinical cases, in our daily practice we might face bone defi ciency to replace missing teeth with dental implants instead of doing second surgery and bone augmentation. We can be more conservative depending on orthodontic means such as; extrusion of hopeless teeth, in other cases, can be used in mini implants to adjust the complicated orthodontic cases and surgical cases such as skeletal open bite or interocclusal space defi ciency. This lecture is for all the implantologists, orthodontists and general practitioners. In this lecture, I will talk about clinical cases to show the interrelation between ortho, implant, aesthetic dentistry and aesthetic medicine for solving clinical cases with no surgery. It’s for specialist dentist and general practitioner. Cases in the lecture will cover: 1) Extrusion of hopeless anterior centrals to correct bone level before replacing them with dental implant instead of bone augmentation; 2) to gain more interocclussal space by intrusion of opposite posterior teeth; 3) to correct skeletal open bite by using mini implant instead of orthognathic surgery; 4) using mini implant to align tilted teeth to provide space for implant or bridge and 5) gum smile treatment by mini implant and Botox beside some cases about aesthetic dentistry.
Ahmed ElSebaai
Mansoura University, Egypt
Title: Effects of resin application on white spot lesions (laboratory study)
Time : 12:45-13:15
Biography:
Ahmed ElSebaai is currently working as Professor of Department of Pediatric Dentistry at Mansoura University-Mansoura- Egypt.
Abstract:
Aim: Th e aim of this study was to evaluate the effect of resin infiltrant on white spot lesions compared to adhesive resin.
Methods: Artificial white spot lesions were created on the labial surfaces of 65 anterior permanent teeth. 31 teeth (Group A white lesion) were divided into three groups according to treatment applied: control A1, ICON A2 and adhesive A3. Th e remaining 34 teeth were immersed in a staining solution. The stained lesions were bleached (Group B) then divided to three groups: control B1, ICON bleached B2 and adhesive resin bleached B3. Th e teeth were photographed at three stages and photos were analyzed to evaluate the color diff erence ΔE between the lesion area and sound enamel before and aft er treatment using image soft ware analysis. Th en, Vickers micro-hardness test was done for the whole teeth aft er treatment.
Results: The ICON A2 group showed a highly significant color improvement (P=<0.0001) compared to the other groups. The other test groups also showed significant color improvement but not as the ICON group. Icon group A2 showed the highest surface microhardness.
Conclusion: Resin infiltrant is an eff ective microinvasive approach in masking white spot lesions much more than adhesive resin.
Mostafa Ahmed Abd El Shafi
Mansoura University, Egypt
Title: Evaluations of a bulk fill composite restorative material using two different curing lights
Time : 14:30-15:00
Biography:
Mostafa Ahmed Abd El Shafi has completed his BDS in 2010 and MSc in 2015. Currently, he is a PHD student at Mansoura University, Egypt and working as Assistant Lecturer in the Department of Dental Biomaterials, Faculty of Dentistry Mansoura University, Egypt.
Abstract:
This study evaluates a bulk fill resin composite by comparing it with a conventional build up one, using two different curing lights, regarding; Degree of Conversion (DC), microleakage, micro hardness and fracture toughness. Two nanohybrid resin composites were investigated; Tetric N-Ceram Bulk Fill and Tetric N-Ceram. Specimens of each type were divided into two equal groups: Group A cured with Quartz Tungsten Halogen (QTH) and Group B cured with light-emitting diode (LED). DC, microleakage, micro hardness and fracture toughness of different groups were studied. The Chi-Square test and t-test were then used to analyze and compare the results statistically. Results show that, there were no signifi cant diff erences among the materials tested and additionally, none of the used curing lights had a more prominent effect on the properties of the tested composites.
Arup Ratan Choudhury
Arup Ratan Choudhury, Dentistry Ibrahim Medical College, Bangladesh
Title: Dental Care and Managements of Medically Compromised Patients in Practise
Time : 16:15-16:45
Biography:
Professor Dr. Arup Ratan Choudhury BDS, PhD, FDSRCS (England), FICCDE, FICOOC Recipient of National Award - EKUSHE PODOK Professor of Dentistry Ibrahim Medical College. Honorary Senior Consultant Department of Dentistry. BIRDEM (WHO Collaborative centre) Dhaka – 1000, Bangladesh. Founder President, MANAS (Association for the Prevention of Drug Abuse)
Abstract:
Diabetes mellitus is known to cause micro vascular and possibly macro vascular completions. Similarly Extensive periodontal disease is associated with increased C- reactive protein (CRP) levels in otherwise healthy, middle aged adults. Periodontal disease seems to influence the occurrence and the severity of coronary artery disease and increases the risk of heart attack or stroke. Different studies proposes two hypotheses, one is that periodontal pathogens could enter the bloodstream, invaded blood vessel walls and ultimately cause atherosclerosis. Another hypothesis shows that periodontal infections can be correlated with increased plasma levels of inflammation such as C-reactive protein. Indeed the periodontal signs & symptoms are now recognized as the sixth complication of diabetes. CRP predicts not only heart disease, but also the risk of developing type 2 diabetes. Individuals with CRP levels greater than 3 mg/L have a risk of getting diabetes 4 to 6 times higher than individuals with lower levels of CRP. Moderate elevation of CRP has been found to be a predictor of increased risk for CVD. Elevated CRP levels in periodontal patients have been reported by several groups. In this study, we examined whether CRP plasma are increased in periodontitis.